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Would Bartholomew die now — merely from touching the man who writhed and groaned in his delirious fever? If so, the matter was out of his hands, and he could not, in all conscience, abandon the victims of the foul disease to their suffering. He and Colet had agreed.

While, all over the land, physicians were fleeing towns and villages for secluded houses in the country, Bartholomew and Colet had decided to stand firm. Bartholomew had nowhere to flee in any case — and all his family and friends were in Cambridge.

Bartholomew braced himself and completed his examination. Besides the swellings in the arms, there were similar lumps, the size of small eggs, in the man's groin and smaller swellings on his neck. He was also burning with fever, and screamed and writhed when Bartholomew gently felt the buboes.

Bartholomew sat back on his heels. Behind him, Mistress Bowman hovered worriedly. 'What is it, Doctor?' she whispered. Bartholomew did not know how to tell her.

'Did he travel alone?' he asked.

'Oh, no! There were three of them. They all came back together.'

Bartholomew's heart sank. 'Where do the others live?' he asked.

Mistress Bowman stared at him. 'It is the pestilence,' she whispered, looking down at her son with a mixture of horror and pity. 'My son has brought the pestilence.'

Bartholomew had to be sure before an official pronouncement was made, and before people started to panic. He stood. "I do not know, Mistress,' he said softly. "I have never seen a case of the pestilence before, and we should check the other lads before we jump to conclusions.'

Mistress Bowman grabbed his sleeve. 'Will he die?' she cried, her voice rising. 'Will my boy die?'

Bartholomew disentangled his arm and took both her hands in his firmly. He stood that way until her shuddering panic had subsided. "I do not know, Mistress.

But you will do him no good by losing control of yourself.

Now, you must fetch clean water and some linen, and sponge his face to bring his fever down.'

The woman nodded fearfully, and went off to do his bidding. Bartholomew examined the young man again. He seemed to be getting worse by the minute, and Bartholomew knew that he would soon see scores of cases of such suffering — perhaps even among those he loved — and be unable to do anything about it.

Mistress Bowman returned with her water and Bartholomew made her repeat his instructions. "I do not wish to frighten you,' he said, 'but we must be careful. Do not allow anyone in the house, and do not go out until I return.' She had gathered her courage while she had been busy, and nodded firmly, reminding him suddenly of Agatha.

He left the house and went to Holy Trinity Church.

He asked the priest if he could borrow a pen and a scrap of parchment, and hurriedly scribbled a note to Gregory Colet at Rudde's Hostel, telling him of his suspicions and asking him to meet him at the Round Church in an hour. Outside, he threw a street urchin a penny and told him to deliver the note to Colet, who would give him another penny when he received it. The lad sped off while Bartholomew trudged to the house of one of the other men who had travelled from London.

As he arrived, he knew that any attempt he might make to contain the disease would be futile. Wails and howls came from within and the house was thronged with people. He elbowed his way through them until he reached the man lying on the bed. A glance told Bartholomew that he was near his end. He could scarcely draw breath and his arms were stuck out because of the huge swellings in his armpits. One had burst, and emitted a smell so foul that some people in the room covered their mouths and noses with scraps of cloth.

'How long has he been ill?' he asked an old woman, who sat weeping in a corner. She refused to look at him, and went on with her wailing, rocking back and forth.

'God's anger is visited upon us!' she cried. 'It will take all those with black, sinful hearts!'

And a good many others besides, thought Bartholomew.

He and Colet had listened carefully to all the stories about the plague that flooded into Cambridge in the hope of learning more. For months, people had spoken of little else. First, itwas thought that the infection would never reach England. After all, how could the foul winds that carried the disease cross the waters of the Channel? But cross they did, and in August, a sailor died of the plague in the Dorset port of Melcombe, and within days, hundreds were dead.

When the disease reached Bristol, officials tried to cut the port off from the surrounding areas to prevent the disease from spreading. But the wave of death was relentless. It was soon in Oxford, and then in London.

Bartholomew and his colleagues discussed it deep into the night. Was it carried by the wind? Was it true that a great earthquake had opened up graves and the pestilence came from the uncovered corpses? Was it a visitation from God? What were they to do if it came to Cambridge? Colet argued that people who had been in contact with plague victims should stay away from those who had not, but even as Colet's words of warning rang in his ears, Bartholomew saw that such a restriction was wholly impractical. Among the crowd was one of

Michaelhouse's servants — even if Bartholomew avoided contact with the scholars, the servant would be among them. And what of those who had already fled?

Thomas Exton, the town's leading physician, declared that none would die if everyone stayed in the churches and prayed. Colet had suggested that applying leeches to the black swellings that were purported to grow under the arms and in the groin might draw off the poisons within. He said he meant to use leeches until his fellow physicians discovered another treatment.

Bartholomew argued that the leeches themselves might spread the infection, but agreed to try them if Colet could prove they worked.

Bartholomew pulled himself out of his thoughts and slammed the door, silencing wailing and whispering alike.

'How long has this man been ill?' he repeated.

There was a gabble of voices answering him, and Bartholomew bent towards a woman dressed in grey.

'He was ill when they came home the night before last,' she said. 'He had been drinking in the King's Head tavern on the High Street, and his friends brought him back when he began to shake with this fever.'

Bartholomew closed his eyes in despair. The King's Head was one of the busiest taverns in the town, and, if the rumours were true and infection spread on the wind, then those who had been in contact with the three young men were already in danger. A hammering on the door stilled the buzz of conversation, and a thickset man in a greasy apron forced his way in.

'Will and his mother are sick,' he yelled. 'And one of Mistress Barnet's babies has turned black!'

There was an immediate panic. People crossed themselves, the window shutters were thrown open, and some began to climb out screaming that the plague was there. Rapidly, only the sick man, Bartholomew, and the woman in grey were left in the house. Bartholomew looked at her closely, noting a sheen of sweat on her face.

He pulled her into the light and felt under her jaw. Sure enough, there were the beginnings of swellings in her neck; she was already infected.

He helped her up the stairs to a large bed, and covered her with blankets, leaving a pitcher of water near her, for she was complaining of a fierce thirst. He went to look at the young man downstairs on his way out, and saw that he was already dead, his face a dark purple and his eyes starting from his face. The white shirt under his arms was stained with blood and with black and yellow pus. The stench was terrible.