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It was impossible to tell how many members the University lost. At the first sign of the plague, some left the town and did not return. As the numbers of deaths rose, harried clerks began to lose count, and many people ended up in the plague pits without any record being made. By January, King's Hall lost ten of its scholars, and Michaelhouse lost eleven.

Bartholomew had thought that perhaps the scholars might fare better than the townspeople because they were younger, fitter, and usually better fed. But the plague struck indiscriminately, and by Christmas the old commoners were still alive and well, but several healthy young students were dead.

However much Bartholomew thought and studied and worked, he could not understand why some people died and others recovered, or why, in the same household, some people caught the disease while others remained healthy, even after being in contact with the sick. He and Colet compared experiences regularly, and argued endlessly and without conclusion. Colet had given up leeching buboes, and incised them where he could, like Bartholomew. But he still believed that leeching after the incisions caused the recovery of his patients.

Bartholomew believed the keys were rest, a warm bed, and clean water. Since neither had a better record of success than the other, each refused to adopt the other's methods. But Colet's patients were generally wealthy, with warm homes and clean bedding. Bartholomew's patients were poor, and warmth and cleanliness were not always easy to attain.

Bartholomew continued on his rounds, lancing the black swellings whenever he thought it might ease a patient's pain. Two more physicians died, and another two fled, so that only Bartholomew, Colet, and Simon Roper from Bene't Hostel were left. They found they could not trust the town officials to carry out their recommendations and had to supervise virtually everything, from the digging of the pits and the proper use of lime, to the cleaning of the streets of the dead rats and refuse that built up.

Bartholomew, arriving home at dawn after staying with a family that had five of seven children dying, was awoken within minutes by hammering on the door.

Wearily, he struggled out of bed to answer it. A young man stood there, his long, unruly hair at odds with his neat scholar's tabard.

"I thought you would have been up by now,' said the man cheekily.

'What do you want?' Bartholomew asked thickly, so tired he could barely speak.

"I have been sent to fetch you to St Radegund's.'

Bartholomew's blood ran cold, and he was instantly awake. 'Why, what has happened?' he asked in a whisper, almost afraid to ask. 'Is it Philippa Abigny?'

'Oh, no,' said the student. 'A man wants you. But you had better hurry up or he said you will be too late.'

Bartholomew hastened back inside to dress. When he emerged, the tousle-haired man was leaning against the wall chatting to the porter. Bartholomew ignored him and made his way up St Michael's Lane at a steady trot. He heard footsteps behind him, and the young man caught him and tried to match his pace.

'If you want to travel quickly, why do you not take a horse?' he asked between gasps.

"I do not have a horse,' answered Bartholomew.

'Who has asked for me? Is it Giles Abigny?' The fear he felt earlier returned. He hoped Abigny had not become ill and gone to the convent for help. St Radegund's had escaped lightly until now, perhaps because the Prioress had determined on a policy of isolation, and no one was allowed in; money in a pot of vinegar was left outside the gates for all food that was delivered. Bartholomew hoped the Prioress had managed to continue so, not only because Philippa was inside, but also because he wanted to know if the plague could be averted in this way.

'You do not have a horse?' queried the student, losing his stride. 'A physician?'

'Who asked for me?' Bartholomew asked again. He was beginning to be annoyed.

"I do not know, just some man. I am only the messenger.'

Bartholomew increased his speed, and quickly left the student puffing and wheezing behind him. It was only a matter of moments before the walls of St Radegund's loomed up out of the early morning mist. He pounded on the door, leaning against the wall to get his breath, his legs unsteady from a brisk run on an empty stomach and anticipation of what was to come.

A small grille in the door snapped open. 'What do you want?' came a sharp voice.

'It is Matthew Bartholomew. I was sent for,' he gasped.

'Not by us,' and the grille slammed shut.

Bartholomew groaned and banged on the door again. There was no reply.

'You are unlikely to get an answer now.'

Bartholomew spun round, and the student found himself pinned against the wall by the throat. 'Hey! I am only the messenger!' he croaked, eyes wide in his face.

Bartholomew relented and loosened his grip, although not by much.

'Who sent for me?' he asked again, his voice dangerously quiet.

"I do not know his name. I will have to show you,' the student said, trying to prise Bartholomew's hands from his throat, some of his former cockiness gone.

He led the way around the walls towards the convent gardens. 'My name is Samuel Gray,' he said.

Bartholomew ignored him. "I am a medical student at Bene't Hostel.'

Bartholomew saw they were heading for a small shack where garden tools were kept. He and Philippa had sheltered there from a summer thunderstorm once as they had walked together among the fruit bushes.

That had been only a few short months before, but to Bartholomew it seemed in another lifetime. Gray reached the hut first, and pushed open the door. Bartholomew took a step inside and peered into the gloom, trying to see what was inside.

'Philippa!' She was kneeling in a corner next to a figure lying on the floor.

'Matt!' She leapt to her feet, and before Bartholomew could prevent her, she had thrown herself into his arms. His first instinct was to force her away, lest he carried the contagion with him somehow in his clothes, but the shack was already rank with the smell of the plague, so there was little point. He allowed all else to be driven from his mind as he enjoyed the first contact he had had with Philippa since the plague began.

Suddenly she pushed him away. 'What are you doing here?' she said. 'Who asked you to come?'

Bartholomew gazed at her in confusion. He looked around at Gray, who stood at the door looking as surprised as Bartholomew.

"I do not know,' Gray said. 'It was a man. He told me to bring you here, and that he would be waiting to meet you.'

Bartholomew looked back at Philippa. "I do not know of any man,' she said. "I have been here since dawn. I had a message to come, and I found Sister Clement here. She has the plague.'

'But who told you to come? And how did you get out? I thought the convent was sealed.' "I do not know, to answer your first question. A message came written on a scrap of parchment pushed under the door. I came here immediately. In answer to your other question, there is a small gate near the kitchens that is always open, although few know of it.

Sister Clement has been using it regularly to slip out and go among the poor.' Her voice caught, and Bartholomew put his arms round her again.

He said nothing while she sobbed quietly, and Gray shuffled his feet in the doorway. On the floor, Sister Clement was near the end, her laboured breathing almost inaudible. Philippa looked at her, and raised her eyes pleadingly to Bartholomew. 'Can you help her?'

Bartholomew shook his head. He had seen so many similar cases during the last few weeks that he did not even need to examine her to know that there was nothing he could do. Even lancing the swellings at this point would do no more than cause unnecessary suffering.