In 2005, WADA, the World Anti-Doping Agency, took caffeine off its list of banned substances. Several studies have found performance-enhancing benefits from caffeine ingestion, several others have found no effect of caffeine ingestion on endurance performance, and at least one study found caffeine ingestion to be related to reduced performance. The differences in these results may be partly explained by differences in individuals’ responsiveness to caffeine and the nuances of the study designs.
Extrapolating from run-to-exhaustion studies in the lab, the likely benefit of taking caffeine is in the range of 1 to 2 percent (perhaps 20 to 50 seconds in a 10K or 90 seconds to 4 minutes in a marathon). Caffeine may not work as well during races as in lab tests because one of its effects is an increase in epinephrine (adrenaline) levels, which are also stimulated by the excitement of competition, so the caffeine effect may be reduced during a race.
The effects of caffeine that may boost performance for marathoners are a glycogen-sparing effect, an increase in the release of calcium in muscle fibers, and stimulation of the central nervous system. Ingesting caffeine mobilizes fatty acids that allow you to use more fat and less glycogen at a given pace, meaning your glycogen stores last longer. Instead of your hitting the wall at 23 miles (37 km) because of glycogen depletion, caffeine ingestion could theoretically allow your glycogen stores to last the full marathon distance.
The primary effect of caffeine in improving endurance performance may be stimulation of the central nervous system, which increases alertness and concentration. There is intriguing evidence that central nervous system stimulation reduces perception of effort so that a given pace feels easier.
Our view is that runners should use caffeine only if they are already trying every other legal option to improve running performance. This includes training hard and intelligently, having an excellent diet, and working to optimize all the other lifestyle factors that influence running performance. If you are doing everything else right, and your personal ethics permit it, then a low dose of caffeine may allow you to gain a small improvement in performance.
The side effects of caffeine include headaches, dizziness, anxiety, nervousness, gastrointestinal distress, and heart palpitations. Caffeine is also a mild laxative, which can be particularly inconvenient during a race.
Athletes vary widely in their sensitivity to, and tolerance of, caffeine, so you are an experiment of one. If you do not regularly consume caffeine, you will likely be more sensitive to the effects. If you decide to use caffeine for your marathon, practice using it during your longest training run to see how your body responds.
Attempting to do high-mileage or high-intensity training in hot weather is a physiological challenge that requires you to be flexible with your training schedule. By planning your training, you can minimize the impact of hot weather. Start each workout fully hydrated by making rehydration a priority after the previous day’s run. Run at the time of day when the weather is the least taxing on your body. On a hot, humid day, slow your pace from the outset rather than waiting until your body forces you to slow.
The main fuels for endurance exercise are carbohydrate and fat. Protein also provides a small amount of energy. Carbohydrate supplies the majority of energy during exercise, and fat supplies the bulk of the remainder. If you want to run 26.2 miles (42.2 km) at a good pace, you had better like carbohydrate foods because they’ll be the mainstay of your diet during day-to-day training and especially in the few days before the marathon.
Even if you’re a gaunt marathoner, your body has a large stockpile of energy in the form of fat. A 140-pound (63 kg) runner with a body-fat level of 6 percent still carries around 8.4 pounds (3.8 kg) of fat. Each pound of fat supplies 3,500 calories of energy, so this individual has more than 29,000 calories stored as fat.
For the purposes of fast marathoning, of course, what matters are your carbohydrate, not fat, stores, and your carbohydrate reserves are much more limited. If you do a good job of carbohydrate loading, you can store about 2,000 to 2,500 calories of glycogen (the body’s storage form of carbohydrate).
When you run, your body burns a mixture of carbohydrate and fat. The harder you run, the higher the proportion of carbohydrate you use; the slower you run, the higher the proportion of fat you use. During walking, more than half of the calories you burn are provided by the breakdown of fat. As your pace increases, you use proportionately less fat and more carbohydrate. An easy recovery run may be fueled by 65 percent carbohydrate and 35 percent fat. If you race the marathon, approximately 75 to 90 percent of the fuel you use is supplied by the breakdown of carbohydrate. For those jogging the marathon, the proportion of carbohydrate used would be somewhat lower.
Carbohydrate is a more efficient energy source than fat. The breakdown of fat requires more oxygen per calorie released than does carbohydrate. Because fat doesn’t produce energy aerobically as efficiently as carbohydrate does, you can’t run as fast burning just fat. Your body uses several strategies to keep you from running out of carbohydrate stores. One of these strategies is to use relatively more fat as your carbohydrate stores become low. Anyone who has hit the wall knows the joys of this “strategy.” A problem with glycogen depletion is that there aren’t warning signs that it’s going to occur until it’s too late. When you need to slow suddenly in a marathon, the culprit is probably glycogen depletion, not dehydration, which tends to affect you more gradually.
You can prevent carbohydrate depletion by glycogen loading. Glycogen loading (also known as carbohydrate loading) is the practice of manipulating your diet and training to increase your glycogen stores.
Marathoners can almost double their muscle glycogen stores by doing a long run 7 days before a race, then eating a low-carbohydrate diet for 3 days, followed by a high-carbohydrate diet (70 to 80 percent of calories from carbohydrate) for the 3 days before the race. The long run depletes your body’s glycogen stores, and the 3 days of low carbohydrate intake keep them low. This triggers a mechanism in your body to store as much glycogen as possible. When you eat a high-carbohydrate diet during the last 3 days before the marathon, therefore, your body stores an extra supply of glycogen.
This classic approach to glycogen loading has fallen out of favor as we’ve learned more about tapering for marathons. Carbohydrate depletion recently has been shown to suppress the immune system, so the classic glycogen depletion and loading regimen increases your risk of getting sick when you can least afford it. Also, a 20-miler (32 km) 1 week before your marathon carries too much risk, in the form of lingering fatigue or soreness, for the benefits it brings to your carbohydrate loading. (Besides, what marathoner wants to avoid carbohydrate for 3 days?)
The good news is that glycogen stores can be elevated to similar levels without the long run and low-carbohydrate phases of the original glycogen-loading diet. All you need to do is eat a normal diet up until the last 3 days before the race and taper your training program to about half your normal training load. Then eat a high-carbohydrate diet the last 3 days and do a short, slow run on those days. Your body will store glycogen to almost the same level as if you did the whole regimen of glycogen depletion and loading.
Rice, pasta, bread, sweet potatoes, pancakes, bagels, potatoes, corn, and raisins are excellent sources of carbohydrate. Many of the world’s best marathoners eat rice for their prerace meal because it provides plenty of carbohydrate and is easy to digest. Expect to gain a couple of pounds and feel slightly bloated when you glycogen load because your body stores 2.6 grams of water for every gram of glycogen. The added weight is just extra fuel to help get you through the marathon, and the stored water will help prevent dehydration as the marathon progresses.