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The sway of alcohol over mankind is unquestionably due to its power to stimulate the mystical faculties in human nature, usually crushed to earth by the cold facts and dry criticisms of the sober hour. Sobriety diminishes, discriminates and says no. Drunkenness expands, unites and says yes. It is in fact the great exciter of the Yes function in man. It brings its votary from the chill periphery of things into the radiant core. It makes him for the moment one with truth. Not through mere perversity do men run after it. To the poor and the unlettered it stands in the place of symphony concerts and literature; and it is part of the deeper mystery and tragedy of life that whiffs and gleams of something that we immediately recognize as excellent should be vouchsafed to so many of us only through the fleeting earlier phases of what, in its totality, is so degrading a poison. The drunken consciousness is one bit of the mystic consciousness, and our total opinion of it must find its place in our opinion of that larger whole.

William James was not the first to detect a likeness between drunkenness and the mystical and premystical states. On the day of Pentecost there were people who explained the strange behavior of the disciples by saying, “These men are full of new wine.”

Peter soon undeceived them: “These are not drunken, as ye suppose, seeing it is but the third hour of the day. But this is that which was spoken by the prophet Joel. And it shall come to pass in the last days, saith God, I will pour out of my Spirit upon all flesh.”

And it is not only by “the dry critics of the sober hour” that the state of God-intoxication has been likened to drunkenness. In their efforts to express the inexpressible, the great mystics themselves have done the same. Thus, St. Theresa of Avila tells us that she “regards the center of our soul as a cellar, into which God admits us as and when it pleases Him, so as to intoxicate us with the delicious wine of His grace.”

Every fully developed religion exists simultaneously on several different levels. It exists as a set of abstract concepts about the world and its governance. It exists as a set of rites and sacraments, as a traditional method for manipulating the symbols, by means of which beliefs about the cosmic order are expressed. It exists as the feelings of love, fear and devotion evoked by this manipulation of symbols.

And finally it exists as a special kind of feeling or intuition—a sense of the oneness of all things in their divine principle, a realization (to use the language of Hindu theology) that “thou art That,” a mystical experience of what seems self-evidently to be union with God.

The ordinary waking consciousness is a very useful and, on most occasions, an indispensable state of mind; but it is by no means the only form of consciousness, nor in all circumstances the best. Insofar as he transcends his ordinary self and his ordinary mode of awareness, the mystic is able to enlarge his vision, to look more deeply into the unfathomable miracle of existence.

The mystical experience is doubly valuable; it is valuable because it gives the experiencer a better understanding of himself and the world and because it may help him to lead a less self-centered and more creative life.

In hell, a great religious poet has written, the punishment of the lost is to be “their sweating selves, but worse.” On earth we are not worse than we are; we are merely our sweating selves, period.

Alas, that is quite bad enough. We love ourselves to the point of idolatry; but we also intensely dislike ourselves—we find ourselves unutterably boring. Correlated with this distaste for trie idolatrously worshiped self, there is in all of us a desire, sometimes latent, sometimes conscious and passionately expressed, to escape trom the prison of our individuality, an urge to self-transcendence. It is to this urge that we owe mystical theology, spiritual exercises and yoga—to this, too, that we owe alcoholism and drug addiction.

Modern pharmacology has given us a host of new synthetics, but in the field of the naturally occurring mind changers it has made no radical discoveries. All the botanical sedatives, stimulants, vision revealers, happiness promoters and cosmic-consciousness arousers were found out thousands of years ago, before the dawn of history.

In many societies at many levels of civilization attempts have been made to fuse drug intoxication with God intoxication. In ancient Greece, for example, ethyl alcohol had its place in the established religion. Dionysus, or Bacchus, as he was often called, was a true divinity. His worshipers addressed him as Lusios, “Liberator,” or as Theoinos, “God-wine.” The latter name telescopes fermented grape juice and the supernatural into a single pentecostal experience. “Born a god,” writes Euripides, “Bacchus is poured out as a libation to the gods, and through him men receive good.” Unfortunately they also receive harm. The blissful experience of self-transcendence which alcohol makes possible has to be paid for, and the price is exorbitantly high.

Complete prohibition of all chemical mind changers can be decreed, but cannot be enforced, and tends to create more evils than it cures. Even more unsatisfactory has been the policy of complete toleration and unrestricted availability. In England, during the first years of the eighteenth century, cheap untaxed gin—“drunk for a penny, dead drunk for two-pence”—threatened society with complete demoralization. A century later, opium, in the form of laudanum, was reconciling the victims of the Industrial Revolution to their lot—but at an appalling cost in terms of addiction, illness and early death. Today most civilized societies follow a course between the two extremes of total prohibition and total toleration. Certain mind-changing drugs, such as alcohol, are permitted and made available to the public on payment of a very high tax, which tends to restrict their consumption. Other mind changers are unobtainable except under doctors’ orders—or illegally from a dope pusher. In this way the problem is kept within manageable bounds. It is most certainly not solved. In their ceaseless search for self-transcendence, millions of would-be mystics become addicts, commit scores of thousands of crimes and are involved in hundreds of thousands of avoidable accidents.

Do we have to go on in this dismal way indefinitely? Up until a few years ago, the answer to such a question would have been a rueful “Yes, we do.” Today, thanks to recent developments in biochemistry and pharmacology, we are offered a workable alternative. We see that it may soon be possible for us to do something better in the way of chemical self-transcendence than what we have been doing so ineptly for the last seventy or eighty centuries.

Is it possible for a powerful drug to be completely harmless? Perhaps not. But the physiological cost can certainly be reduced to the point where it becomes negligible. There are powerful mind changers which do their work without damaging the taker’s psychophysical organism and without inciting him to behave like a criminal or a lunatic. Biochemistry and pharmacology are just getting into their stride. Within a few years there will probably be dozens of powerful but—physiologically and socially speaking—very inexpensive mind changers on the market.

In view of what we already have in the way of powerful but nearly harmless drugs; in view, above all, of what unquestionably we are very soon going to have—we ought to start immediately to give some serious thought to the problem of the new mind changers. How ought they to be used? How can they be abused? Will human beings be better and happier for their discovery? Or worse and more miserable?

The matter requires to be examined from many points of view. It is simultaneously a question for biochemists and physicians, for psychologists and social anthropologists, for legislators and law-enforcement officers. And finally it is an ethical question and a religious question. Sooner or later—and the sooner, the better—the various specialists concerned will have to meet, discuss and then decide, in the light of the best available evidence and the most imaginative kind of foresight, what should be done. Meanwhile let us take a preliminary look at this many-faceted problem.

Last year American physicians wrote 48,000,000 prescriptions for tranquilizing drugs, many of which have been refilled, probably more than once. The tranquilizers are the best known of the new, nearly harmless mind changers. They can be used by most people, not indeed with complete impunity, but at a reasonably low physiological cost. Their enormous popularity bears witness to the fact that a great many people dislike both their environment and “their sweating selves.” Under tranquilizers the degree of their self-transcendence is not very great; but it is enough to make all the difference, in many cases, between misery and contentment.