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2. T. Friedmann and R. Roblin, “Gene therapy for human genetic disease?,” Science 175, (1972): 949–955, https://science.sciencemag.org/content/175/4025/949.long.

3. JapanPrize, “2015 Japan Prize Commemorative Lecture: Dr. Theodore Friedmann & Prof. Alan Fischer,” YouTube video, 1:07:56, last viewed June 7, 2020, https://www.youtube.com/watch?v=Z5SLxpPLxcw&t=136s.

4. David Baltimore, “Limiting science: A biologist’s perspective,” Daedalus, 107, (1978): 37–45, https://www.jstor.org/stable/20024543?seq=1.

5. M. J. Cline, “Perspectives for gene therapy: inserting new genetic information into mammalian cells by physical techniques and viral vectors,” Pharmacology & Therapeutics 29, (1985): 69–92.

6. P. Jacobs, “Doctor tried gene therapy on 2 humans,” Washington Post, October 8, 1980, https://www.washingtonpost.com/archive/politics/1980/10/08/doctor-tried-gene-therapy-on-2-humans/c95d4b44-3e5c-4a48-904c-4bbefe52391b/?utm_term=.b867c1010e22.

7. D. Bartels, “Gene therapy: scientific advances and socio-ethical considerations,” Journal of Social & Biological Structures 9, (1986) 105–113, https://psycnet.apa.org/record/1987-32279-001.

8. E. Beutler, “The Cline affair,” Molecular Therapy 4, (2001): 396–397. https://www.cell.com/action/showPdf?pii=S1525-0016%2801%2990486-1.

9. R. Williamson, “Gene therapy,” Nature 298, (1982): 416–418, https://www.nature.com/articles/298416a0.

10. W. F. Anderson, “Prospects for human gene therapy,” Science 226, (1984): 401–409, https://science.sciencemag.org/content/226/4673/401.long.

11. P. Gorner and J. Lyon, “Altered Fates,” Chicago Tribune, March 7, 1986, https://www.chicagotribune.com/news/ct-xpm-1986-03-07-8601170568-story.html.

12. Jonathan Gardner, “New estimate puts cost to develop a new drug at $1B, adding to long -running debate,” BioPharma Dive, March 3, 2020, https://www.biopharmadive.com/news/new-drug-cost-research-development-market-jama-study/573381/.

13. Larry Thompson, “Human gene therapy debuts at NIH,” Washington Post, September 15, 1990, https://www.washingtonpost.com/archive/politics/1990/09/15/human-gene-therapy-debuts-at-nih/f98ffb56-aa7f-4529-a5f6-c57cb845a7cd/?utm_term=.82d9fd43ca22.

14. Jeff Lyon and Peter Gomer, Altered Fates: Gene Therapy and the Retooling of Human Life (New York: W. W. Norton & Co., 1996).

15. Robin Marantz Henig, “Dr. Anderson’s gene machine,” New York Times, March 31, 1999, https://www.nytimes.com/1991/03/31/magazine/dr-anderson-s-gene-machine.html.

16. Peter Gorner, “Doctors begin world’s first gene therapy,” Chicago Tribune, September 15, 1990, http://articles.chicagotribune.com/1990-09-15/news/9003170543_1_dr-w-french -anderson-gene-therapy-adenosine-deaminase.

17. L. M. Muul et al., “Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial,” Blood 101, (2003): 2563–2569, https://pubmed.ncbi.nlm.nih.gov/12456496/.

18. J. M. Wilson, “Recollections from a Pioneer Who Provided the Foundation for the Success of Gene Therapy in Treating Severe Combined Immune Deficiencies,” Human Gene Therapy 27, (2016): 53–56, https://www.liebertpub.com/doi/10.1089/humc.2016.29013.int.

19. T. Friedmann, “A brief history of gene therapy,” Nature Genetics 2, (1992): 93–98, https://www.nature.com/articles/ng1092-93.

20. Natalie Angier, “Gene experiment to reverse inherited disease is working,” New York Times, April 1, 1994, https://www.nytimes.com/1994/04/01/us/gene-experiment-to-reverse-inherited-disease-is-working.html.

21. S. H. Orkin and A. G. Motulsky, “Report and recommendations of the panel to assess the NIH investment in research on gene therapy,” OSP, December 7, 1995, https://osp.od.nih.gov/wp-content/uploads/2014/11/Orkin_Motulsky_Report.pdf.

22. T. Friedmann, “Preface,” in The Development of Human Gene Therapy (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1999).

23. Paul Gelsinger, “Jesse’s Intent,” http://www.jesse-gelsinger.com/jesses-intent.html.

24. Rick Weiss and Deborah Nelson, “Teen dies undergoing experimental gene therapy,” Washington Post, September 29, 1999, https://www.washingtonpost.com/wp-srv/WPcap/1999-09/29/060r-092999-idx.html?noredirect=on.

25. Sheryl Gay Stolberg, “The biotech death of Jesse Gelsinger,” New York Times, November 28, 1999, https://www.nytimes.com/1999/11/28/magazine/the-biotech-death-of-jesse-gelsinger.html.

26. S. E. Raper et al., “Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adnoviral gene transfer,” Molecular Genetics and Metabolism 80, (2003): 148–158, https://pubmed.ncbi.nlm.nih.gov/14567964/.

27. Peter Little, Genetic Destinies (Oxford, UK: Oxford University Press, 2002).

28. Siddhartha Mukherjee, The Gene: An Intimate History (New York: Simon & Schuster, 2017).

29. The Gene, PBS 2020, https://www.pbs.org/show/gene/.

30. H. F. Judson, “The Glimmering Promise of Gene Therapy.” MIT Technology Review, November 1, 2006, https://www.technologyreview.com/s/406797/the-glimmering-promise-of-gene-therapy/.

31. Ibid.

32. K. Davies, “From the Cultural Revolution to the Gene Therapy Revolution: An Interview with Guangping Gao, PhD,” Human Gene Therapy, February 14, 2020, https://www.liebertpub.com/doi/abs/10.1089/hum.2020.29109.int.