9. “Chinese ministry to investigate gene-edited babies claim,” People’s Daily, November 28, 2018, http://en.people.cn/n3/2018/1128/c90000-9523145.html.
10. Open letter, “122 scientists issued a joint statement: strongly condemned ‘the first immune AIDS gene editor,’ ” November 26, 2018, https://www.yicai.com/news/100067069.html.
11. Bloomberg QuickTake News, “CRISPR Co-Inventor Slams Claims of Gene-Edited Babies,” YouTube video, 2:02, last viewed June 2, 2020, https://www.youtube.com/watch?v=bk-1UEkxzVo.
12. Emmanuelle Charpentier, email, December 7, 2018.
13. Al Jazeera English, “#CRISPRbabies: What’s the future of gene editing? | The Stream,” YouTube video, 25:40, last viewed June 2, 2020, https://www.youtube.com/watch?v=E989S8P0pKc.
14. Antonio Regalado, “CRISPR inventor Feng Zhang calls for moratorium on gene-edited babies,” MIT Technology Review, November 26, 2018, https://www.technologyreview.com/2018/11/26/66361/crispr-inventor-feng-zhang-calls-for-moratorium-on-baby-making/.
15. Kathy Niakan, “Expert reaction to Jiankui He’s defence of his work,” Science Media Centre, November 28, 2018, http://www.sciencemediacentre.org/expert-reaction-to-jiankui-hes-defence-of-his-work/.
16. Francis Collins, “Statement on claim of first gene-edited babies by Chinese researcher,” The NIH Director (blog), November 28, 2018, https://www.nih.gov/about-nih/who-we-are/nih-director/statements/statement-claim-first-gene-edited-babies-chinese-researcher.
17. C. Wang et al., “Gene-edited babies: Chinese Academy of Medical Sciences’ response and action,” Lancet 393, (2019): 25–26, https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)33080-0/fulltext.
18. Paul Knoepfler, “He Jiankui didn’t really gene edit those girls; he mutated them,” The Niche, December 4, 2018, https://ipscell.com/2018/12/he-jiankiu-didnt-really-gene-edit-those-girls-he-mutated-them/.
19. J. Savulescu, “Monstrous gene editing experiment,” Practical Ethics (blog), November 26, 2018, http://blog.practicalethics.ox.ac.uk/2018/11/press-statement-monstrous-gene-editing-experiment/.
20. Derek Lowe, “After Such Knowledge,” In the Pipeline (blog), November 28, 2018, https://blogs.sciencemag.org/pipeline/archives/2018/11/28/after-such-knowledge.
21. Kevin Davies, “CRISPR’s China Crisis,” Genetic Engineering & Biotechnology News, January 11, 2019, https://www.genengnews.com/insights/crisprs-china-crisis/.
22. Organizing Committee of the Second International Summit on Human Genome Editing, “On Human Genome Editing II,” National Academies of Sciences, Engineering, Medicine, November 29, 2018, http://www8.nationalacademies.org/onpinews/newsitem.aspx?RecordID=11282018b.
23. Luke W. Vrotsos, “Chinese Researcher Who Said He Gene-Edited Babies Breaks Week of Silence, Vows to Defend Work,” Harvard Crimson, December 7, 2018, https://www.thecrimson.com/article/2018/12/7/harvard-profs-react-to-human-gene-edit/.
24. E. Chen and P. Mozur, “Chinese scientist who claimed to make genetically edited babies is kept under guard,” New York Times, December 28, 2018, https://www.nytimes.com/2018/12/28/world/asia/he-jiankui-china-scientist-gene-editing.html.
25. Steve Lombardi, phone interview, July 23, 2019.
26. Kevin Davies, “He Jiankui Fired in Wake of CRISPR Babies Investigation,” Genetic Engineering & Biotechnology News, January 21, 2019, https://www.genengnews.com/news/he-jiankui-fired-in-wake-of-crispr-babies-investigation/.
27. Zach Coleman and Michelle Chan, “Chinese ‘baby editing’ scientist retreats from flagship company,” Nikkei Asian Review, July 16, 2019, https://asia.nikkei.com/Business/Biotechnology/Chinese-baby-editing-scientist-retreats-from-flagship-company.
28. Dan Cloer, “Genetically modified babies: An insider’s view,” Vision, August 13, 2019, https://www.vision.org/interview-william-hurlbut-genetically-modified-babies-insiders-view-8975.
29. Jennifer Doudna, “He Jiankui,” Time 100, April 2019, http://time.com/collection/100-most-influential-people-2019/5567707/he-jiankui/.
Chapter 18: Crossing the Germline
1. Ed Yong, “The CRISPR baby scandal gets worse by the day,” Atlantic, December 3, 2018, https://www.theatlantic.com/science/archive/2018/12/15-worrying-things-about-crispr-babies-scandal/577234/.
2. The He Lab, “Why we chose HIV and CCR5 first,” YouTube video, 2:59, last viewed June 2, 2020, https://www.youtube.com/watch?v=aezxaOn0efE.
3. P. Tebas, “Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV,” New England Journal of Medicine 370, (2014): 901–910, https://www.nejm.org/doi/full/10.1056/NEJMoa1300662.
4. Rick Mullin, “On crossing an ethical line in human genome editing,” Chemical & Engineering News, December 12, 2018, https://cen.acs.org/biological-chemistry/genomics/crossing-ethical-line-human-genome/96/web/2018/12.
5. Sean Ryder, “#CRISPRbabies: Notes on a scandal,” CRISPR Journal 1, (2018): 355–357, https://doi.org/10.1089/crispr.2018.29039.spr.
6. Ibid.
7. R. Lovell-Badge, “CRISPR babies: a view from the centre of the storm,” Development, (February 2019): 146, http://dev.biologists.org/content/146/3/dev175778.
8. H. Greely, “He Jiankui, embryo editing, CCR5, the London patient, and jumping to conclusions,” STAT, April 15, 2019, https://www.statnews.com/2019/04/15/jiankui-embryo-editing-ccr5/.