17. Alex Philippidis, “COVID-19 Drug & Vaccine Candidate Tracker,” Genetic Engineering & Biotechnology News, May 18, 2020, https://www.genengnews.com/covid-19-candidates/covid-19-drug-and-vaccine-tracker/.
18. T. R. Abbott et al., “Development of CRISPR as a prophylactic strategy to combat novel coronavirus and influenza,” bioRxiv, March 14, 2020, https://www.biorxiv.org/content/10.1101/2020.03.13.991307v1.
19. Jennifer Doudna, “Biochemist Explains How CRISPR Can Be Used to Fight COVID-19,” Amanpour, March 30, 2020, http://www.pbs.org/wnet/amanpour-and-company/video/biochemist-explains-how-crispr-can-be-used-to-fight-covid-19/.
20. Lorrie Moore, “Bioperversity,” New Yorker, May 12, 2003, https://www.newyorker.com/magazine/2003/05/19/bioperversity.
21. Christof Koch, The Quest for Consciousness (Englewood, CO: Roberts & Co., 2004).
INDEX
A note about the index: The pages referenced in this index refer to the page numbers in the print edition. Clicking on a page number will take you to the ebook location that corresponds to the beginning of that page in the print edition. For a comprehensive list of locations of any word or phrase, use your reading system’s search function.
A
Abbott Laboratories, 173
Abramson Cancer Center, 166
Abudayyeh, Omar, 100
Acrigen Biosciences, 102
Adeno-associated viruses (AAV), 99, 121, 145–146, 149, 159, 162–165, 172, 331, 335–336
Adverum Biotechnologies, 164
Age of Living Machines, The, 303
Aging, premature, 322, 330, 344–345
Aging, reversing, 12, 280, 345
Agriculture, 6, 38, 101, 301–320, 361
Agrobacterium, 304
AIDS, 117–118, 173, 215–216, 226, 246, 251, 310
Akbari, Omar, 294
Al Jazeera, 238
Albany Medical Center, 153
Alexander, Lamar, 10–11
Alien, 19
Allen, Jenny, 354–355
Alley, Kirstie, 90
Allison, Anthony, 154
Altered Fates, 137
Altshuler, David, 84
Alzheimer’s disease, 12, 80, 164, 269, 280, 344–345
American Scientist, 129
American Society for Microbiology, 63
America’s Got Talent, 147
Ames, Bruce, 130
Amicus Therapeutics, 163
Amino acids, 77, 99, 110, 130–134, 145, 154, 248, 322–323, 327
Amoasii, Leonela, 176–177
Amphibian Foundation, 286
Amyotrophic lateral sclerosis (ALS), 15, 159
Anderson, William French, 132–134, 137–140, 148, 151
Anderson Cancer Center, 175
Ando, Dale, 116
Andromeda Strain, The, 132
Angelman syndrome, 85
Angier, Natalie, 140
ANGPTL3, 331, 344, 345
Antioch College, 107
Anzalone, Andrew, 332–335
AquaBounty, 316
Archimedes, 331
Arizona State University, 221
Arlotta, Paola, 79
Armstrong, Neil, 30
Arnold, Frances, 291
Arnold, John, 161
Artificial intelligence, 349–350
Ash, Caroline, 44
Ashley, Euan, 208
Asimov, Isaac, 103
Astellas Pharma, 165
Ataxia telangiectasia, 363
Atlantic, 245
Atwood, Margaret, 281, 342
Audentes Therapeutics, 164, 165
Austen, Jane, 19
Autism, 79, 80, 157
Avery, Oswald, 135
AveXis, 159–162
Avila Therapeutics, 171
Axel, Richard, 58–59
B
Babies
CRISPR babies, x–xviii, 5, 15–16, 193–205, 214, 230–253, 257–264, 269–276, 338, 354–356
designer babies, xvii–xviii, 5, 11, 204, 215, 223, 341, 348
digital babies, 338
mosaicism and, 199, 220, 248–249, 262–263, 339
Bacillus subtilus, 44
Back to the Future, 19
Bacteria
CRISPR-Cas9 and, 22–28, 23
immune system and, xi–xii, 5, 36–38, 41–45, 50–61
viruses and, xvi–xvii, 5–6, 22–27, 38, 41–45, 50–61, 366
Bacteriophage insensitive mutants (BIM), 41, 44
Bacteriophages, 22–23, 23, 41, 44, 162, 367. See also Phages
Baer, Neal, 6
Baltimore, David, x, 114, 116, 136, 200, 233, 241, 253–254
Banfield, Jill, 49–55, 99
Bannister, Roger, 139
Barn, Gulzaar, 357–358
Barnard, Christiaan, 218
Barrangou, Rodolphe, 21, 42–45, 52, 55–57, 68–70, 81–82, 87, 95–98, 152, 173–175, 178, 180, 205, 258, 320
Base editing, 5, 99, 190, 275, 326–336, 353
Bassey, Nnimmo, 295, 314
Batten disease, 363
Bayer, 302, 308, 314
Baylis, Françoise, 272, 275, 353
Baylor College, 173
BCL11A, 157, 168
Beadle, George, 132
Beam Therapeutics, 329, 330, 336
Becker muscular dystrophy, 176
Begley, Sharon, 334
Beijing Genomics Institute (BGI), 209–211, 226, 266, 268, 350
Bell Laboratories, 183
Benioff Children’s Hospital, 120
Bennett, Jean, 145, 147–151, 176, 273
Berg, Jeremy, 113
Berg, Paul, 253, 272
Berger, James, 173
Berkeley, xiii, 8, 29, 45–45, 49, 50–55, 64–67, 71, 74, 92–95, 138, 145, 151–152, 179, 183, 187, 205, 220, 249, 323, 331, 365
Bermingham, Nessan, 173–175
Bernardi, Sharon, 213
Berry, Andrew, xvi
Best, Friedrich, 151
Beta thalassemia, 120, 136, 152, 155–157, 169–170, 197
Beutler, Ernest, 137
Bier, Ethan, 293
Bingbing, Fan, 242
Biohackers, xii, 196, 264–265, 300
Bio-IT World, 80, 211, 212
BioLife, 159
BioRxiv, 240
Biotechnology, xiii, 4, 12, 23, 46, 181, 221, 268, 304, 308, 345, 367
Bioterrorism, 101
Birney, Ewan, 307
Blaese, Michael, 139–140
Blair, Tony, 17
Blood diseases, xvii, 16, 114, 120, 136, 156, 164. See also Sickle-cell disease
Bloomberg, 237
Bluebird Bio, 156
Boguski, Mark, 77
Bolotin, Alexander, 38, 41, 45
Bolt, Adam, 25
Bondy-Denomy, Joseph, 101–102
Bone marrow transplant, 118–119, 167–170, 194
Book of life, xi, 15, 17–19, 48, 321, 341
Borlaug, Norman, 303
Bosarge, Ed, 12
Bosley, Katrine, 11, 13, 171, 172
Bosley, Richard, 171
Boston Children’s Hospital, 84–85, 157, 363
Boston Globe, 89, 355
Botstein, David, 112
Bourne Identity, The, 239
Boyaval, Patrick, 44
Boyden, Ed, 78
Boyer, Herb, 111
Bradley, Allan, 177
BRAIN Initiative, 78
Brand, Stewart, 286, 288
Brave New World, x, 124, 233, 254, 341, 355, 362
BRCA1, xiii–xiv, 138, 224
BRCA2, 224, 340
Breakthrough, xiii–xiv, 138
Breast cancer gene, xiii–xiv, 138, 224, 340, 351
Brenner, Sydney, 1, 92, 121, 133
Bridges, Jeff, 279
“Brief History of Gene Therapy, A,” 140
Brin, Sergey, 95
Brint, Alan, 149
Brint, Betsy, 149
Brint, David, 149
Broad, Edythe, 3, 91
Broad, Eli, 3, 91
Broad Institute, xii, xvii, 3–4, 7, 75, 80–85, 91–93, 171, 179–186, 190, 295, 319, 323–325, 348