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You don’t have to score the winning goal in the World Cup Final to feel such sensations. If you receive an unexpected promotion at work, and start jumping for joy, you are reacting to the same kind of sensations. The deeper parts of your mind know nothing about football or about jobs. They know only sensations. If you get a promotion, but for some reason don’t feel any pleasant sensations – you will not feel satisfied. The opposite is also true. If you have just been fired (or lost a decisive football match), but you are experiencing very pleasant sensations (perhaps because you popped some pill), you might still feel on top of the world.

The bad news is that pleasant sensations quickly subside and sooner or later turn into unpleasant ones. Even scoring the winning goal in the World Cup Final doesn’t guarantee lifelong bliss. In fact, it might all be downhill from there. Similarly, if last year I received an unexpected promotion at work, I might still be occupying that new position, but the very pleasant sensations I experienced on hearing the news disappeared within hours. If I want to feel those wonderful sensations again, I must get another promotion. And another. And if I don’t get a promotion, I might end up far more bitter and angry than if I had remained a humble pawn.

This is all the fault of evolution. For countless generations our biochemical system adapted to increasing our chances of survival and reproduction, not our happiness. The biochemical system rewards actions conducive to survival and reproduction with pleasant sensations. But these are only an ephemeral sales gimmick. We struggle to get food and mates in order to avoid unpleasant sensations of hunger and to enjoy pleasing tastes and blissful orgasms. But nice tastes and blissful orgasms don’t last very long, and if we want to feel them again we have to go out looking for more food and mates.

What might have happened if a rare mutation had created a squirrel who, after eating a single nut, enjoys an everlasting sensation of bliss? Technically, this could actually be done by rewiring the squirrel’s brain. Who knows, perhaps it really happened to some lucky squirrel millions of years ago. But if so, that squirrel enjoyed an extremely happy and extremely short life, and that was the end of the rare mutation. For the blissful squirrel would not have bothered to look for more nuts, let alone mates. The rival squirrels, who felt hungry again five minutes after eating a nut, had much better chances of surviving and passing their genes to the next generation. For exactly the same reason, the nuts we humans seek to gather – lucrative jobs, big houses, good-looking partners – seldom satisfy us for long.

Some may say that this is not so bad, because it isn’t the goal that makes us happy – it’s the journey. Climbing Mount Everest is more satisfying than standing at the top; flirting and foreplay are more exciting than having an orgasm; and conducting groundbreaking lab experiments is more interesting than receiving praise and prizes. Yet this hardly changes the picture. It just indicates that evolution controls us with a broad range of pleasures. Sometimes it seduces us with sensations of bliss and tranquillity, while on other occasions it goads us forward with thrilling sensations of elation and excitement.

When an animal is looking for something that increases its chances of survival and reproduction (e.g. food, partners or social status), the brain produces sensations of alertness and excitement, which drive the animal to make even greater efforts because they are so very agreeable. In a famous experiment scientists connected electrodes to the brains of several rats, enabling the animals to create sensations of excitement simply by pressing a pedal. When the rats were given a choice between tasty food and pressing the pedal, they preferred the pedal (much like kids preferring to play video games rather than come down to dinner). The rats pressed the pedal again and again, until they collapsed from hunger and exhaustion.36 Humans too may prefer the excitement of the race to resting on the laurels of success. Yet what makes the race so attractive is the exhilarating sensations that go along with it. Nobody would have wanted to climb mountains, play video games or go on blind dates if such activities were accompanied solely by unpleasant sensations of stress, despair or boredom.37

Alas, the exciting sensations of the race are as transient as the blissful sensations of victory. The Don Juan enjoying the thrill of a one-night stand, the businessman enjoying biting his fingernails watching the Dow Jones rise and fall, and the gamer enjoying killing monsters on the computer screen will find no satisfaction remembering yesterday’s adventures. Like the rats pressing the pedal again and again, the Don Juans, business tycoons and gamers need a new kick every day. Worse still, here too expectations adapt to conditions, and yesterday’s challenges all too quickly become today’s tedium. Perhaps the key to happiness is neither the race nor the gold medal, but rather combining the right doses of excitement and tranquillity; but most of us tend to jump all the way from stress to boredom and back, remaining as discontented with one as with the other.

If science is right and our happiness is determined by our biochemical system, then the only way to ensure lasting contentment is by rigging this system. Forget economic growth, social reforms and political revolutions: in order to raise global happiness levels, we need to manipulate human biochemistry. And this is exactly what we have begun doing over the last few decades. Fifty years ago psychiatric drugs carried a severe stigma. Today, that stigma has been broken. For better or worse, a growing percentage of the population is taking psychiatric medicines on a regular basis, not only to cure debilitating mental illnesses, but also to face more mundane depressions and the occasional blues.

For example, increasing numbers of schoolchildren take stimulants such as Ritalin. In 2011, 3.5 million American children were taking medications for ADHD (attention deficit hyperactivity disorder). In the UK the number rose from 92,000 in 1997 to 786,000 in 2012.38 The original aim had been to treat attention disorders, but today completely healthy kids take such medications to improve their performance and live up to the growing expectations of teachers and parents.39 Many object to this development and argue that the problem lies with the education system rather than with the children. If pupils suffer from attention disorders, stress and low grades, perhaps we ought to blame outdated teaching methods, overcrowded classrooms and an unnaturally fast tempo of life. Maybe we should modify the schools rather than the kids? It is interesting to see how the arguments have evolved. People have been quarrelling about education methods for thousands of years. Whether in ancient China or Victorian Britain, everybody had his or her pet method, and vehemently opposed all alternatives. Yet hitherto everybody still agreed on one thing: in order to improve education, we need to change the schools. Today, for the first time in history, at least some people think it would be more efficient to change the pupils’ biochemistry.40