CHAPTER 9
The dead can speak. It just takes time and patience to learn their language. Dr. Lucy Abruzzo had spent her career studying this language, and as White Memorial’s chief of pathology, she spoke it better than anyone on staff. These days, bureaucracy and administrative duties took precedence over the lab work that had fed her passion for years. Lucy’s personality was better suited to working with tissue samples and cadavers than to managing budgets, personalities, and cost structures. But hospital CEO Roman Janowski was not somebody you turned down twice.
As a manager, she remained somewhat of an enigma. A detached personality, someone a bit aloof, she was well suited to the autopsy table, but around a conference room table that personality could be off-putting. Lucy was an infrequent contributor to any pre-meeting banter. Most jokes and pop culture references were lost on her, as someone who did not own a television. Away from the lab, Lucy read nonfiction compulsively, ran for distance, loved chess, and enjoyed cooking, but only when following a recipe. Improvisation was for wilderness medicine.
It was common for Lucy to be so overscheduled with meetings that she never had time for any actual pathology. Weekends were different, though. Lucy used Sundays to catch up on paperwork and assist in the lab. Someone was always here doing something.
The moment Lucy set foot in the lab, a powerful scent hit her nostrils. Someone was testing stool samples, probably looking for a toxin. The pathology lab was always full of unusual smells, and Lucy found them all oddly pleasing. Dr. Becca Stinson, a fresh-faced second-year pathology resident, waved Lucy over to her workstation.
Some cases Lucy’s team managed were difficult to crack, while others were more straightforward. The pathology of the human body could be like the mystery novels Lucy once favored. Bodies had unreliable narrators, red herrings, good guys and villains, and answers that could be proved beyond a reasonable doubt using the right tools and investigative logic. The case Becca was working was evidently a tough one to solve.
Lucy pushed her shoulder-length brown hair away from her narrow face and put on her tortoiseshell glasses so she could read the case file Dr. Stinson handed her. It looked straightforward.
Becca, who trained at a CrossFit gym and discussed it incessantly, had about four inches and twenty pounds (all muscle) on Lucy, whose arms and neck were thin from years of running. Though she was petite, Lucy probably could have held her own in the CrossFit arena. Years of cutting ribs and sawing bones had built up a lot of strength in those delicate arms.
Lucy studied the file intently for several quiet moments, her focus unwavering, the noxious odor no longer even registering.
The doctor’s report was succinct, just the way Lucy liked it.
The patient, Cliff Anderson, seventy-seven, has experienced progressive cognitive decline and increased incidents of lethargy, depression, and memory troubles. The patient has presented with decreased motor function, as exhibited by multiple recent falls at home. Physical and neurological examinations were both unremarkable. CT and MRI scans of the head did not reveal significant acute pathology and the EEG was negative for seizure-like activity. Cerebral angiography also negative for abnormalities. Temporal artery biopsy ordered to rule out temporal arteritis.
That last line was Mr. Anderson’s last best hope. If the vessels that supplied blood to the man’s head were inflamed or damaged, it could cause his symptoms. The condition was also completely treatable. However, Lucy believed the real culprit behind Mr. Anderson’s troubles was something no department at White Memorial could cure. The biopsy did in fact show inflammation, some possible blockage there. But sometimes lab results offered rays of false hope. The symptoms outlined in the report were standard for another ailment, one that would be heartbreaking for both Mr. Anderson and his family.
“Well?” Becca asked after Lucy had finished her review.
“Seems cut and dried to me. Mr. Anderson has Alzheimer’s.”
Alzheimer’s disease had no official test that could be done on the living. Neuropathological signs of the disease, amyloid plaques and neurofibrillary tangles of tau, a protein involved in maintaining the internal structure of the nerve cell, could be confirmed only during autopsy. Diagnoses of Alzheimer’s relied largely on documenting mental decline. The medical report indicated symptoms consistent with that diagnosis, and given the patient’s advanced age, Lucy figured it would have been Becca’s first best guess as well.
“You don’t seem convinced,” Lucy said.
Becca buried her hands inside the pockets of her lab coat. “He’s not presenting in a typical fashion.”
“How so?”
“The tissue sample from the temporal artery biopsy showed severe inflammation, more than I expected, and some evidence of tissue death. Also, the patient complained of headaches and anxiety.”
“And you think it could be-what? His MRI was normal. No evidence of stroke, tumor, head injury, nothing structural like hydrocephalus.”
“Even without excess fluid in the brain, at minimum we should order an erythrocyte sedimentation rate, and I’d like to do a toxicology screen as well.”
“Which the insurance company is going to deny.”
“Which is why I want your help,” Becca said.
“Charm them with my infectious personality, is that it?”
Becca cleared her throat. “Well, something like that, I suppose.” Clearly, Becca felt she was on to something, but pathologists were not supposed to treat patients like internists.
Lucy appreciated this doctor’s doggedness, respected it. She also understood her frustration. The pathology lab, hidden in the bowels of White Memorial, was stocked with cutting-edge pathology equipment including cryostat machines, tissue processors, imaging systems, and a digital incubator. It was a large and well-lit space, complete with several workstations, each equipped with a powerful microscope. The lab could run almost any test or diagnostic requested by hospital doctors, but not without somebody to foot the bill. Like many hospitals its size, White Memorial operated on razor-thin margins, scrutinizing every penny.
Lucy considered her options. She knew one test would lead to another, and then another. Cliff Anderson’s doctor would come storming back here, pissed at having to do battle with the insurance company for tests he did not order.
“It’s Alzheimer’s, dammit. What don’t you get?”
The thought put a rare smile on Lucy’s face. Becca was right to question the dearth of testing, and the tissue death, while not indicative of temporal arteritis, was still unusual. Why not do some more tests? Lucy asked herself. After all, didn’t Mr. Anderson deserve the best that White Memorial had to offer?
“Let’s do whatever tests you think are necessary,” Lucy said. “We’ll sort it all out later.”
Becca’s broad smile was the big win of the day. Lucy loved her team, and it felt good to see them feel successful. Pathology was hardly a lonely profession, though many held that belief. A good path lab required smart docs like Becca to operate at a high level. What it did not require was direct involvement with patient care, and this suited Lucy just fine.
From down the hall, Lucy heard the familiar sound of gurney wheels on approach. It was a bellwether of sorts-the dead were coming. They showed up here even on Sundays.
Sure enough, Jordan Cobb, the six-foot-two hospital diener and longtime White Memorial employee, poked his head into the lab.
“Hey there, Docs,” Jordan said.
The diener always had a happy expression on his face despite the grim nature of his job. It was Jordan’s responsibility to collect the dead, move them to the morgue down the hall from the pathology lab, and clean each body prior to autopsy. It was a necessary job, but one many found unsettling. Not Jordan, though. He was unemotional about the work, the way Lucy would have been.