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And it will have babies.

Adult guinea worms may be invisible to your immune system, but their kids have a different strategy—they set off every alarm they can.

Why? Well, overexcited immune defenses are tricky, painful, dangerous things. With all those baby guinea worms raising a ruckus, your infected leg becomes inflamed. Huge blisters appear, which makes you run screaming to the nearest pond to cool them down.

Very clever. The young guinea worms smell the water and pop out of the blisters. Then they settle down to begin their wait for the next unwary drinker of pond water.

Ew, yuck, repeat.

Guinea worms have been pulling this trick for a long time. In fact, it was thousands of years ago that ancient healers found out how to cure them. The procedure is simple, in theory. Just pull the adult worms out of the victim’s leg. But there’s a trick: If you pull too quickly, the worm breaks in half, and the part left inside rots away, causing a terrible infection. The patient usually dies.

Here’s how the doctors of the ancient world did it:

Carefully draw one end of the worm out, and wrap it around a stick. Then, over the next seven days or so, wind the guinea worm outward, like reeling in a fish in very slow motion. That’s right: It takes seven days. Don’t rush! It won’t be the most enjoyable week you ever spent, but at the end you’ll have your body back in good working order. And you’ll also have a stick with a wormy thing wrapped around it.

And this icky leftover will become the symbol of medicine.

Ew.

But maybe it’s not such a weird symbol. Historians figure that guinea-worm removal was the first-ever form of surgery. Back then, it was probably a pretty amazing feat, pulling a snake out of a human body. Maybe the doctors hung the snake-wrapped stick on their walls afterward, just to show that they could get the job done.

So the next time you’re at the doctor’s office, be on the lookout for this heartwarming symbol of the ancient healing arts. (And don’t believe all that crap about the great god Hermes; it’s all about the guinea worms.)

Chapter 23

WORM

“Stay here,” I said.

“What’s up?”

“I smell something.”

Lace frowned. “Dude. It’s not me, is it?”

“No! Hush.” I squatted, pressing my palms flat against the trembling platform. The shudder in the graffitied concrete built, then gradually faded again, tacking toward us, back and forth through the warrens of the Underworld. The hairs on the back of my neck pricked up, sensing a low and shuddering note hanging in the air, the same vast moan I’d heard below the exhaust towers.

“Cal? What the hell?”

“I think something’s coming.”

Something? Not a train?”

“I don’t know what it is, except that it’s part of all this craziness. And it’s old and big, and … getting closer.”

A crumbling exit sign pointed up a set of stairs, but I knew from Hunting 101 that it had been long since paved over. We would have to run back to Union Square along the tracks.

But first I needed a weapon.

I brushed past Lace and through the bathroom stall, kicking away the last pieces of wood clinging to one corner of its metal frame. I wrenched the seven feet of rust-caked iron from the crumbling cement and weighed it in my hands. Brutal and straightforward.

“What about me?” Lace said from the doorway.

“What about you?”

“Don’t I get a club-thingy?”

“Lace, you couldn’t even pick this up. You don’t have superpowers yet.”

She scowled at me and lifted a fragment of rusty iron from the floor. “Well, whatever’s coming, it’s not catching me empty-handed. It smells like death.”

“You can smell it? Already?”

“Duh.” She sniffed and made a face. “Dead rat on steroids.”

I blinked. Lace was changing faster than any peep I’d ever seen, as if the new strain was mutating at some hyped-up pace, changing as it moved from host to host. Or maybe the beastie simply smelled bad. The stench was overpowering now, sending signals of alarm and fury coursing through my body. Though my mind screamed run, my muscles were itching for a fight.

And somehow, I was certain they were going to get one. My instincts sang to me that the creature knew we were here; it was hunting us.

“Let’s go,” I said.

We jumped from the platform, landing with a crunch on the gravel bed. As we dashed headlong up the tracks, the lights of the next station glimmered along the curved rails, seeming to pull away from us as we ran. It was only four blocks; and I told myself we were going to make it.

Then I saw—through one of the bolt holes that workers jump into if they get caught by an approaching train—a blackness deeper than the subway tunnel’s gloom. A hole in the earth. A few yards closer, a cold draft hit us, goose-pimpling my flesh and carrying another wave of the beast’s smell.

“It’s coming,” Lace said, nose in the air. She had come to a halt, holding her foot-long piece of iron high, as if she were going to stake a vampire. But this was bigger than any peep, and I was fairly sure that it didn’t have a heart.

“Stay behind me,” I said. I pointed toward the opening. “It’ll come out of there.”

Her eyes peered into the blacker-than-black space for a moment. “So what is this thing again?”

“Like I said, I don’t…” My voice trailed off, an answer dawning on me. Not so much words or images, but a feeling—a generations-forgotten dread, an enemy long buried, a warning never to lose the old knowledge, because the sun can’t always protect us from what lives in the lower depths. I felt again the shuddering revelation from my first biology courses, that the natural world is less concerned with our survival than we ever admit. As individuals, even as a species—we are here on borrowed time, and death is as cold and dark and permanent as the deepest fissures in the stones we walk on.

“What is it, Cal?” Lace asked again.

“It’s the reason we’re here.” I swallowed. The words came from my mouth unbidden. “Why peeps are here.”

She nodded gravely. “Is that why I want to kill it so much?”

I might have answered her, but I didn’t get a chance, because the thing finally showed its face—if you could call it that. The white-pale, squirming shape emerged into the tunnel without eyes or nose, or discernable top or bottom, just a mouth—a ring of spikes set in a glistening hole, like the maw of some mutant and predatory earthworm, adapted to chew through rock as easily as flesh.

Segments ran down its length, like a rat’s tail, and I wondered for a moment if this was just a part of a much greater monster. This white, gelatinous mass emerging from the tunnel might have been its head, or a clawed tentacle, or a bulbous and spiny tongue; I couldn’t tell. All I knew was what the parasite inside me wanted: My constant hunger had turned suddenly to boundless energy—attack, the parasite demanded.

In a blind fury, I ran toward the beast, the rusty iron in my hands hissing through the air like ancient hatred.

The eyeless beast sensed me coming, its body flinching away, and the tip of my swinging iron barely scraped its flesh, tearing a stringy tendril from its side, which unraveled like a thread pulled from a garment. The tendril flailed angrily, but no blood gushed—all that flowed from the wound was another wave of the beast’s smell.

While I teetered off balance, it struck back, the mouth shooting toward me on a column of pale flesh. I stumbled backward, and the teeth reached their limit a few short inches from my leg, gnashing wetly at the air before snapping back into the beast.