He began his literary career in 1979 with Code Name November (originally published as The November Man), the book that became an international sensation and introduced the cool American spy who later gave rise to a whole series. His second novel, Public Murders, a Chicago police procedural, won the Edgar® Award from the Mystery Writers of America in 1981.
In all, Bill Granger published thirteen November Man novels, three nonfiction books, and nine novels. In 1980, he began weekly columns in the Chicago Tribune on everyday life (he was voted best Illinois columnist by UPI), which were collected in the book Chicago Pieces. His books have been translated into ten languages.